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The Distinct Role of HIF-1α and HIF-2α in Hypoxia and Angiogenesis

Hypoxia results in a wide range of adaptive physiological responses, including metabolic reprogramming, erythropoiesis, and angiogenesis. The response to hypoxia at the cellular level is mainly regulated by hypoxia-inducible factors (HIFs): HIF1α and HIF2α isoforms. Although structurally similar and...

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Bibliografiske detaljer
Principais autores: Mouayad Zuheir Bakleh, Ayman Al Haj Zen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-05-01
Serier:Cells
Fag:
Online adgang:https://www.mdpi.com/2073-4409/14/9/673
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