A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma

BackgroundLiquid biopsies do not reflect the complete mutation profile of the tumor but have the potential to identify actionable mutations when tumor biopsies are not available as well as variants with low allele frequency. Most retrospective studies conducted in small cohorts of pediatric cancers...

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Autors principals:	Flora Cimmino, Vito Alessandro Lasorsa, Simona Vetrella, Achille Iolascon, Mario Capasso
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-12-01
Col·lecció:	Frontiers in Oncology
Matèries:	genetic mutation bioinformactics analysis next generation sequencing neuroblastoma liquid biopsy and circulating tumor DNA
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2020.596191/full
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