A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition.
Monoamine transporters (MATs) carry out neurotransmitter reuptake from the synaptic cleft, a key step in neurotransmission, which is targeted in the treatment of neurological disorders. Cholesterol (CHOL), a major component of the synaptic plasma membrane, has been shown to exhibit a modulatory effe...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Public Library of Science (PLoS)
2018-01-01
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| Цуврал: | PLoS Computational Biology |
| Онлайн хандалт: | https://doi.org/10.1371/journal.pcbi.1005907 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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