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The Effect of Cholesterol on Membrane-Bound Islet Amyloid Polypeptide

Islet amyloid polypeptide (IAPP) is a proposed cause of the decreased beta-cell mass in patients with type-II diabetes. The molecular composition of the cell-membrane is important for regulating IAPP cytotoxicity and aggregation. Cholesterol is present at high concentrations in the pancreatic beta-c...

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Bibliografski detalji
Glavni autori: Mikkel Christensen, Nils A. Berglund, Birgit Schiøtt
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021-04-01
Serija:Frontiers in Molecular Biosciences
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fmolb.2021.657946/full
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