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CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Inhibition of the CXXC5–DVL interaction is a potential therapeutic strategy for height enhancement of children with growth retardation. Longitudinal bone growth ceases with growth plate senescence during puberty. However, the molecular mechanisms of this phenomenon are largely unexplored. Here, we e...

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Bibliografiske detaljer
Principais autores: Sehee Choi, Hyun-Yi Kim, Pu-Hyeon Cha, Seol Hwa Seo, Chulho Lee, Yejoo Choi, Wookjin Shin, Yunseok Heo, Gyoonhee Han, Weontae Lee, Kang-Yell Choi
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2019-04-01
Serier:Life Science Alliance
Online adgang:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201800254
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