In vitro and ex vivo evaluation of preclinical models for FAP-targeted theranostics: differences and relevance for radiotracer evaluation

Abstract Background Fibroblast activation protein (FAP) is an attractive target for cancer theranostics. Although FAP-targeted nuclear imaging demonstrated promising clinical results, only sub-optimal results are reported for targeted radionuclide therapy (TRT). Preclinical research is crucial in se...

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Главные авторы:	Circe D. van der Heide, Joana D. Campeiro, Eline A. M. Ruigrok, Lilian van den Brink, Shashikanth Ponnala, Shawn M. Hillier, Simone U. Dalm
Формат:	Artigo
Язык:	Inglês
Опубликовано:	SpringerOpen 2024-12-01
Серии:	EJNMMI Research
Предметы:	Cancer-associated fibroblast (CAF) Fibroblast activation protein (FAP) Targeted radionuclide therapy (TRT) Radionuclide theranostics Preclinical models
Online-ссылка:	https://doi.org/10.1186/s13550-024-01191-6
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