Model-informed evidence for rifapentine use in Chinese HIV-positive adults with latent tuberculosis: Assessing ethnic PK differences and interactions with ritonavir

Background: Ethnic differences in rifapentine pharmacokinetics (PK) between Chinese and non-Chinese populations remain unclear. When co-administered for the treatment of HIV and latent TB infection (LTBI), rifapentine may alter the PK of ritonavir. However, clinical data on rifapentine use in HIV-po...

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Autores principales:	Hongyi Yang, Weijian Liu, Nuo Xu, Wei Li, Wen Yao Mak, Chaozhuang Shen, Liang Zheng, Qingfeng He, Yehua Xie, Xiaoqiang Xiang, Peize Zhang, Xiao Zhu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2026-01-01
Colección:	International Journal of Infectious Diseases
Materias:	Rifapentine Ethnic differences Drug interactions Ritonavir Modeling
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1201971225004515
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