Dolutegravir concentrations in children receiving 3-month weekly isoniazid and rifapentine (3HP) for tuberculosis prevention

ABSTRACT In Tuberculosis Trials Consortium Study 35, which investigated the optimal dosing and safety of once-weekly isoniazid and rifapentine (3HP) in 69 children requiring tuberculosis preventive therapy, 7 children with HIV received 50 mg of once-daily dolutegravir. Plasma dolutegravir concentrat...

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Bibliografiske detaljer

Principais autores:	Ruvarashe J. Madzime, Louvina van der Laan, Samantha du Toit, Shaun Barnabas, Ingrid Courtney, Nicole E. Brown, Rada Savic, Belen P. Solans, Meredith G. Dixon, Lufina Tsirizani, Paolo Denti, Rosanna Boyd, Anneke C. Hesseling
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology 2026-02-01
Serier:	Microbiology Spectrum
Fag:	pharmacokinetics children rifapentine dolutegravir HIV tuberculosis
Online adgang:	https://journals.asm.org/doi/10.1128/spectrum.03303-25
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