lncRNA RP11-199F11.2 promotes high-grade serous ovarian cancer cell proliferation by regulating cuproptosis through FDX1

Abstract To elucidate the expression characteristics of the long noncoding RNA RP11-199F11.2 (RP11) in high-grade serous ovarian cancer (HGSOC) and its potential mechanism of regulating cancer progression via the copper-death pathway, and to evaluate the therapeutic potential of the copper ion carri...

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Detalhes bibliográficos

Principais autores:	Shishi Xu, Linping Wang, Yingying Wu, Yufang Xia, Lingzhi Wang, Xiao Yu, Xin Sun, Yanhui Lou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-11-01
Colecção:	Scientific Reports
Assuntos:	High-grade serous ovarian cancer lncRNA RP11-199F11.2 FDX1 Cuproptosis Inflammatory microenvironment
Acesso em linha:	https://doi.org/10.1038/s41598-025-29080-5
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