Hypothalamic arcuate microglia in sepsis: AgRP circuit engagement and ARHGAP24-dependent remodeling
Abstract Background Sepsis remains a leading cause of death in intensive care, and effective therapies that restore host adaptation are limited. The hypothalamus is a central hub that coordinates endocrine and immune homeostasis, yet how defined hypothalamic microcircuits are engaged in sepsis induc...
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| Główni autorzy: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2026-04-01
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| Seria: | Journal of Neuroinflammation |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12974-026-03786-3 |
| Etykiety: |
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