Echs1-mediated histone crotonylation facilitates zygotic genome activation and expression of repetitive elements in early mammalian embryos

Abstract Histone crotonylation, a conserved post-translational histone modification, plays a crucial role in transcriptional regulation. However, its function in early embryonic development remains largely unexplored. Here, we perform genome-wide mapping of histone crotonylation in mouse and human e...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yong-feng Wang, Yu-ting Wan, Qian-rong Qi, Qing Tian, Xin-mei Liu, Qing-zhen Xie, Ying Yin, Li-quan Zhou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-07-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-60565-z
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!