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Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer

The regulation of gene expression is an integral cellular process orchestrated by epigenetic marks like histone modifications. Perturbations in the activity or abundance of epigenetic factors can lead to tumorigenesis. Remarkably, several metabolites influence the epigenetic landscape in cells. Here...

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Principais autores: Deepak Pant, Parik Kakani, Rushikesh Joshi, Abin Sabu, Shruti Agrawal, Atul Samaiya, Sanjeev Shukla
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2025-08-01
Serier:eLife
Fag:
Head and neck cancer
histone crotonylation
YEATS2
epigenetics
GCDH
EMT
Online adgang:https://elifesciences.org/articles/103321
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