Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
<p>Abstract</p> <p>Background</p> <p>The interferon (IFN)-induced, dsRNA-dependent serine/threonine protein kinase, PKR, plays a key regulatory role in the IFN-mediated anti-viral response by blocking translation in the infected cell by phosphorylating the alpha subunit of elongation factor 2 (eIF2)...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2005-02-01
|
| Schriftenreihe: | Virology Journal |
| Online-Zugang: | http://www.virologyj.com/content/2/1/17 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|