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Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription

<p>Abstract</p> <p>Background</p> <p>HIV-1 Tat protein recruits human positive transcription elongation factor P-TEFb, consisting of CDK9 and cyclin T1, to HIV-1 transactivation response (TAR) RNA. CDK9 is maintained in dephosphorylated state by TFIIH and undergo phosphorylation upon the dissociatio...

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Bibliográfalaš dieđut
Váldodahkkit: Brady John, Debebe Zufan, Washington Kareem, Ammosova Tatyana, Nekhai Sergei
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2005-07-01
Ráidu:Retrovirology
Liŋkkat:http://www.retrovirology.com/content/2/1/47
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