A Potential Blueprint for the Design of Biased Ligands for Aminergic GPCRs
G protein-coupled receptors (GPCRs) are omnipresent in the regulation of physiological processes and therefore account for the most prominent drug target class. However, nearly all drugs targeting GPCRs have been developed by the concept of receptors as simple on–off switches. This is surprising, be...
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| Format: | Artigo |
| Sprog: | Inglês |
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MDPI AG
2022-11-01
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| Serier: | Medical Sciences Forum |
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| Online adgang: | https://www.mdpi.com/2673-9992/14/1/149 |
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