A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates

Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies. PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that express the surface antigen VAR2CSA and bind to chondroitin sulfate A (CSA) in the placenta. Women become PM-resistant over...

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Egile Nagusiak:	Justin YA Doritchamou, Jonathan P Renn, Bethany Jenkins, Almahamoudou Mahamar, Alassane Dicko, Michal Fried, Patrick E Duffy
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	eLife Sciences Publications Ltd 2022-02-01
Saila:	eLife
Gaiak:	pregnancy malaria vaccine VAR2CSA variant blocking antibody
Sarrera elektronikoa:	https://elifesciences.org/articles/76264
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