A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates
Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies. PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that express the surface antigen VAR2CSA and bind to chondroitin sulfate A (CSA) in the placenta. Women become PM-resistant over...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2022-02-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/76264 |
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