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Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing
Abstract Cell cycle progression is governed by complexes of the cyclin-dependent kinases (CDKs) and their regulatory subunits cyclin and Cks1. CDKs phosphorylate hundreds of substrates, often at multiple sites. Multisite phosphorylation depends on Cks1, which binds initial priming phosphorylation si...
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| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Portfolio
2025-05-01
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| シリーズ: | Nature Communications |
| オンライン･アクセス: | https://doi.org/10.1038/s41467-025-59700-7 |
| タグ: |
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