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Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

Abstract Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation. In this study, we synthesized some novel 4H-chromene-3-carbonitr...

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Principais autores: Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli, Aida Iraji
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-09-01
coleção:BMC Chemistry
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Acesso em linha:https://doi.org/10.1186/s13065-024-01305-0
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