Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

Abstract Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation. In this study, we synthesized some novel 4H-chromene-3-carbonitr...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli, Aida Iraji
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-09-01
Edice:	BMC Chemistry
Témata:	Melanogenesis 4H-chromene-3-carbonitrile derivatives Tyrosinase inhibitors Molecular docking Molecular dynamics simulation
On-line přístup:	https://doi.org/10.1186/s13065-024-01305-0
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!