Identification and external validation of a prognostic signature based on N6-methyladenosine- and tertiary lymphoid structures-related genes to evaluate survival prognosis and treatment efficacy in lung adenocarcinoma

Abstract Background The N6-Methyladenosine (m6A) RNA modification critically regulates cancer biology, and tertiary lymphoid structures (TLSs) shape antitumor immunity. However, their combined prognostic roles in lung adenocarcinoma (LUAD) remain unclear. This study applies an integrative multi-omic...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xiangbao Yang, Chengwen Zheng, Yinpeng Pan, Shuoming Wu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer 2025-12-01
Цуврал:	Discover Oncology
Нөхцлүүд:	Tertiary lymphoid structures N6-methyladenosine Lung adenocarcinoma Machine learning Mult omics Prognostic model
Онлайн хандалт:	https://doi.org/10.1007/s12672-025-04318-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!