Identification and external validation of a prognostic signature based on N6-methyladenosine- and tertiary lymphoid structures-related genes to evaluate survival prognosis and treatment efficacy in lung adenocarcinoma

Abstract Background The N6-Methyladenosine (m6A) RNA modification critically regulates cancer biology, and tertiary lymphoid structures (TLSs) shape antitumor immunity. However, their combined prognostic roles in lung adenocarcinoma (LUAD) remain unclear. This study applies an integrative multi-omic...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Xiangbao Yang, Chengwen Zheng, Yinpeng Pan, Shuoming Wu
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Springer 2025-12-01
سلاسل:	Discover Oncology
الموضوعات:	Tertiary lymphoid structures N6-methyladenosine Lung adenocarcinoma Machine learning Mult omics Prognostic model
الوصول للمادة أونلاين:	https://doi.org/10.1007/s12672-025-04318-w
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!