Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway

Abstract Background The JAK/STAT signaling pathway plays a crucial role in the release of interferons (IFNs) and the proinflammatory response during SARS-CoV-2 infection, contributing to the cytokine storm characteristic of severe COVID-19 cases. STAT3, a key protein in this pathway, has been implic...

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Bibliografiset tiedot

Päätekijät:	Nesrine Ebrahim, Hajir A. Al Saihati, Zahraa Alali, Sabry Younis Mohamed Mahmoud, Ali A. Rabaan, Arigue A. Dessouky, Rabab F. Salim, Ashraf A. Shamaa, Ahmed N. Abdallah, Nehal M. Elsherbiny, Gamal Othman, Abdelnaser A. Badawy, Gianpiero Di Leva, Omnia A. Badr
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2025-05-01
Sarja:	Stem Cell Research & Therapy
Aiheet:	COVID-19 MSCs-EVs JAK/STAT signaling pathway MicroRNA
Linkit:	https://doi.org/10.1186/s13287-025-04284-8
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