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HWJMSC-EVs promote cartilage regeneration and repair via the ITGB1/TGF-β/Smad2/3 axis mediated by microfractures

Abstract The current first-line treatment for repairing cartilage defects in clinical practice is the creation of microfractures (MF) to stimulate the release of mesenchymal stem cells (MSCs); however, this method has many limitations. Recent studies have found that MSC-derived extracellular vesicle...

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Príomhchruthaitheoirí: Zhian Chen, Tianhua Zhou, Huan Luo, Zhen Wang, Qiang Wang, Rongmao Shi, Zian Li, Rongqing Pang, Hongbo Tan
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2024-04-01
Sraith:Journal of Nanobiotechnology
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12951-024-02451-2
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