A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage

BackgroundDespite strong historical records on the accuracy of saliva testing, oral fluids are considered poorly suited for pneumococcal carriage detection. We evaluated an approach for carriage surveillance and vaccine studies that increases the sensitivity and specificity of pneumococcus and pneum...

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Auteurs principaux:	Willem R. Miellet, Janieke van Veldhuizen, David Litt, Rob Mariman, Alienke J. Wijmenga-Monsuur, Tessa Nieuwenhuijsen, Jennifer Christopher, Rebecca Thombre, Seyi Eletu, Thijs Bosch, Nynke Y. Rots, Marianne Alice van Houten, Elizabeth Miller, Norman K. Fry, Elisabeth A. M. Sanders, Krzysztof Trzciński
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-04-01
Collection:	Frontiers in Microbiology
Sujets:	Streptococcus pneumoniae (pneumococcus) pneumococcal serotypes pneumococcal carriage saliva quantitative PCR (qPCR)
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1156695/full
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