A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage

BackgroundDespite strong historical records on the accuracy of saliva testing, oral fluids are considered poorly suited for pneumococcal carriage detection. We evaluated an approach for carriage surveillance and vaccine studies that increases the sensitivity and specificity of pneumococcus and pneum...

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Prif Awduron:	Willem R. Miellet, Janieke van Veldhuizen, David Litt, Rob Mariman, Alienke J. Wijmenga-Monsuur, Tessa Nieuwenhuijsen, Jennifer Christopher, Rebecca Thombre, Seyi Eletu, Thijs Bosch, Nynke Y. Rots, Marianne Alice van Houten, Elizabeth Miller, Norman K. Fry, Elisabeth A. M. Sanders, Krzysztof Trzciński
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2023-04-01
Cyfres:	Frontiers in Microbiology
Pynciau:	Streptococcus pneumoniae (pneumococcus) pneumococcal serotypes pneumococcal carriage saliva quantitative PCR (qPCR)
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1156695/full
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