BRCA-associated hereditary male cancers: can gender affect the prevalence and spectrum of germline pathogenic variants?

IntroductionAlthough hereditary male neoplasms are quite rare, individuals harbouring germline BRCA1/2 pathogenic variants (PVs) may have a risk of developing tumours associated with Hereditary Breast and Ovarian Cancer (HBOC) syndrome, including male breast (MBC), prostate (PCa) and pancreatic (PC)...

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Detaylı Bibliyografya
Asıl Yazarlar:	Daniele Fanale, Lidia Rita Corsini, Chiara Brando, Ugo Randazzo, Marco Bono, Erika Pedone, Alessandro Perez, Roberta Sciacchitano, Daniela Cancelliere, Paola Piraino, Ambra Giurintano, Tancredi Didier Bazan Russo, Pietro Ferraro, Gaetana Rinaldi, Valeria Spinnato, Vincenzo Gennusa, Gianfranco Pernice, Salvatore Vieni, Gianni Pantuso, Antonio Russo, Viviana Bazan
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2024-06-01
Seri Bilgileri:	Frontiers in Oncology
Konular:	BRCA1 BRCA2 germline pathogenic variants HBOC male breast cancer melanoma
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1414343/full
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BRCA-associated hereditary male cancers: can gender affect the prevalence and spectrum of germline pathogenic variants?

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