Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity

Glycation, caused by reactive dicarbonyls, plays a role in various diseases by forming advanced glycation end products. In live cells, reactive dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) are produced during cell metabolism, and these should be removed consistently. However, the dicarbo...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Ginga Ito, Yota Tatara, Ken Itoh, Miwa Yamada, Tetsuro Yamashita, Kimitoshi Sakamoto, Takayuki Nozaki, Kinji Ishida, Yui Wake, Takehito Kaneko, Tomokazu Fukuda, Eriko Sugano, Hiroshi Tomita, Taku Ozaki
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2023-01-01
Σειρά:	BBA Advances
Θέματα:	Mitochondria ES1 Reactive dicarbonyl Glyoxalase Methylglyoxal degradation
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2667160323000212
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