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A tissue-targeted prime/pull/keep therapeutic herpes simplex virus vaccine protects against recurrent ocular herpes infection and disease in HLA-A*0201 transgenic rabbits

ABSTRACT Herpes simplex virus type 1 (HSV-1) continues to be one of the most prevalent viral infections globally, with approximately 3.72 billion individuals affected worldwide. A clinical herpes vaccine is still lacking. In the present study, a novel prime/pull/keep vaccine was tested in a human le...

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Principais autores: Aziz A. Chentoufi, Swayam Prakash, Hawa Vahed, Sweta Karan, Afshana Quadiri, Anthony B. Nesburn, Lbachir BenMohamed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2025-05-01
coleção:Journal of Virology
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Acesso em linha:https://journals.asm.org/doi/10.1128/jvi.00135-25
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