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NF-κB/OCT-1 Mediated Upregulation of CXCL14 Chemokine Mobilizes Mucosal Effector Memory CD44+CD62L-CD4+ and CD8+ TEM Cells, and NK Cells Associated with Protection Against Genital Herpes

Background: Mucosal chemokines (eg, CCL25, CCL28, CXCL14, and CXCL17) play key roles in protecting mucosal surfaces against invading infectious pathogens. However, their specific contributions to protection against genital herpes remain to be fully elucidated. Here, we investigated the role of CXCL...

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Principais autores: Yassir Lekbach, Swayam Prakash, Hawa Vahed, Afshana Quadiri, Azizur Rehman, El Houcine El Fatimi, Joshua Christian Dorotta, Baverly Sabathini Suoth, Chhaya Maurya, America Garcia, Gina Park, Lbachir BenMohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Case Western Reserve University 2026-06-01
Colecção:Pathogens and Immunity
Assuntos:
HSV-2
Genital Herpes
CXCL14
Mucosa
Memory CD8+ T Cells
NF-κB
Acesso em linha:https://paijournal.com/index.php/paijournal/article/view/879
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