Platelets induce free and phospholipid-esterified 12-hydroxyeicosatetraenoic acid generation in colon cancer cells by delivering 12-lipoxygenase

Platelets promote tumor metastasis by inducing promalignant phenotypes in cancer cells and directly contributing to cancer-related thrombotic complications. Platelet-derived extracellular vesicles (EVs) can promote epithelial-mesenchymal transition (EMT) in cancer cells, which confers high-grade mal...

Descripció completa

Dades bibliogràfiques

Autors principals:	Annalisa Contursi, Simone Schiavone, Melania Dovizio, Christine Hinz, Rosa Fullone, Stefania Tacconelli, Victoria J. Tyrrell, Rosalia Grande, Paola Lanuti, Marco Marchisio, Mirco Zucchelli, Patrizia Ballerini, Angel Lanas, Valerie B. O'Donnell, Paola Patrignani
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-01-01
Col·lecció:	Journal of Lipid Research
Matèries:	blood platelets 12-HETE 12-Lipoxygenase extracellular vesicles colorectal cancer plasma membrane phospholipids
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227521000912
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!