Comparison Among Modified Continual Reassessment Methods with Different Dose Allocation Methods for Phase I Clinical Trials
The continual reassessment method (CRM) has been an essential Bayesian finding design in phase I clinical trials. It utilizes all the information in observed data which contributes to its essential operational characteristics. However, the CRM has been criticized for its aggressive dose escalation....
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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MDPI AG
2025-03-01
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| Edice: | Mathematics |
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| On-line přístup: | https://www.mdpi.com/2227-7390/13/5/863 |
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