Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans.
In Caenorhabditis elegans (C. elegans), the promotion of longevity by the transcription factor DAF-16 requires reduced insulin/IGF receptor (IIR) signaling or the ablation of the germline, although the reason for the negative impact of germ cells is unknown. FOXO/DAF-16 activity inhibits germline pr...
Gardado en:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2012-01-01
|
| Series: | PLoS Genetics |
| Acceso en liña: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002836&type=printable |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|