Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
Abstract FoxO transcription factors, inhibited by insulin/insulin‐like growth factor signalling (IIS), are crucial players in numerous organismal processes including lifespan. Using genomic tools, we uncover over 700 direct dFOXO targets in adult female Drosophila. dFOXO is directly required for tra...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Nature
2011-06-01
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| Col·lecció: | Molecular Systems Biology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1038/msb.2011.36 |
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