DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO

Abstract Insulin/IGF‐1 signaling controls metabolism, stress resistance and aging in Caenorhabditis elegans by regulating the activity of the DAF‐16/FoxO transcription factor (TF). However, the function of DAF‐16 and the topology of the transcriptional network that it crowns remain unclear. Using ch...

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Bibliografiske detaljer

Principais autores:	Eugene Schuster, Joshua J McElwee, Jennifer M A Tullet, Ryan Doonan, Filip Matthijssens, John S Reece‐Hoyes, Ian A Hope, Jacques R Vanfleteren, Janet M Thornton, David Gems
Format:	Artigo
Sprog:	Inglês
Udgivet:	Springer Nature 2010-08-01
Serier:	Molecular Systems Biology
Fag:	aging C. elegans DAF‐16/FoxO DamID chromatin profiling transcriptional networks
Online adgang:	https://doi.org/10.1038/msb.2010.54
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