ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Abstract Capture Hi-C (CHi-C) is a new technique for assessing genome organization based on chromosome conformation capture coupled to oligonucleotide capture of regions of interest, such as gene promoters. Chromatin loop detection is challenging because existing Hi-C/4C-like tools, which make diffe...

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Autori principali:	Yousra Ben Zouari, Anne M. Molitor, Natalia Sikorska, Vera Pancaldi, Tom Sexton
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2019-05-01
Serie:	Genome Biology
Soggetti:	Promoter-enhancer interactions Chromatin loops Capture Hi-C Biological replicates Gene regulation Chromatin assortativity
Accesso online:	http://link.springer.com/article/10.1186/s13059-019-1706-3
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