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Fine mapping chromatin contacts in capture Hi-C data

Abstract Background Hi-C and capture Hi-C (CHi-C) are used to map physical contacts between chromatin regions in cell nuclei using high-throughput sequencing. Analysis typically proceeds considering the evidence for contacts between each possible pair of fragments independent from other pairs. This...

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Sparad:
Huvudupphov: Christiaan Q Eijsbouts, Oliver S Burren, Paul J Newcombe, Chris Wallace
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2019-01-01
Serie:BMC Genomics
Ämnen:
Capture Hi-C
Chromatin conformation
Bayesian statistics
Variable selection
Länkar:http://link.springer.com/article/10.1186/s12864-018-5314-5
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