A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells
Cyclic dinucleotides are conserved second messengers but current detection methods are limited. Here the authors engineer a Förster resonance energy transfer (FRET) based biosensor, BioSTING, which gives real-time in vitro detection of these nucleotides.
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2020-07-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-020-17228-y |
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