Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides.

The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines. The cyclic dinucleotides can be bacterial second messengers c-di-GMP and c-di-AMP, 3'5'-3'5' cyclic GMP-AMP (3'3' cGAMP) produced by Vibrio ch...

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Hlavní autoři:	Guanghui Yi, Volker P Brendel, Chang Shu, Pingwei Li, Satheesh Palanathan, C Cheng Kao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS ONE
On-line přístup:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0077846&type=printable
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