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Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

Adenosine triphosphate (ATP) represents a danger signal that accumulates in injured tissues, in inflammatory sites, and in the tumor microenvironment. ATP promotes tumor growth but also anti-tumor immune responses notably via the P2X7 receptor. ATP can also be catabolized by CD39 and CD73 ecto-enzym...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Mélanie Demeules, Allan Scarpitta, Romain Hardet, Henri Gondé, Catalina Abad, Marine Blandin, Stephan Menzel, Yinghui Duan, Björn Rissiek, Tim Magnus, Anna Marei Mann, Friedrich Koch-Nolte, Sahil Adriouch
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-10-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012534/full
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