Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type

Acid-sensing ion channels (ASICs) are neuronal Na+-permeable ion channels that are activated by extracellular acidification and are involved in fear sensing, learning, neurodegeneration after ischemia, and in pain sensation. We have recently found that the human ASIC1a (hASIC1a) wild type (WT) clone...

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Egile Nagusiak:	Anand Vaithia, Sabrina Vullo, Zhong Peng, Omar Alijevic, Stephan Kellenberger
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2019-05-01
Saila:	Frontiers in Molecular Neuroscience
Gaiak:	ASIC variant mutation kinetics patch-clamp voltage-clamp fluorometry
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fnmol.2019.00133/full
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