Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type

Acid-sensing ion channels (ASICs) are neuronal Na+-permeable ion channels that are activated by extracellular acidification and are involved in fear sensing, learning, neurodegeneration after ischemia, and in pain sensation. We have recently found that the human ASIC1a (hASIC1a) wild type (WT) clone...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Anand Vaithia, Sabrina Vullo, Zhong Peng, Omar Alijevic, Stephan Kellenberger
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2019-05-01
Sarja:	Frontiers in Molecular Neuroscience
Aiheet:	ASIC variant mutation kinetics patch-clamp voltage-clamp fluorometry
Linkit:	https://www.frontiersin.org/article/10.3389/fnmol.2019.00133/full
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