Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type

Acid-sensing ion channels (ASICs) are neuronal Na+-permeable ion channels that are activated by extracellular acidification and are involved in fear sensing, learning, neurodegeneration after ischemia, and in pain sensation. We have recently found that the human ASIC1a (hASIC1a) wild type (WT) clone...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Anand Vaithia, Sabrina Vullo, Zhong Peng, Omar Alijevic, Stephan Kellenberger
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2019-05-01
Цуврал:	Frontiers in Molecular Neuroscience
Нөхцлүүд:	ASIC variant mutation kinetics patch-clamp voltage-clamp fluorometry
Онлайн хандалт:	https://www.frontiersin.org/article/10.3389/fnmol.2019.00133/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!