The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity

Summary: We characterized circulating extracellular vesicles (EVs) in obese and lean humans, identifying transcriptional cargo differentially expressed in obesity (277 unique genes; false discovery rate < 10%). Since circulating EVs may have broad origin, we compared this obesity EV transcriptome wi...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Emeli Chatterjee, Michael J. Betti, Quanhu Sheng, Phillip Lin, Margo P. Emont, Guoping Li, Kaushik Amancherla, Marta Garcia-Contreras, Priyanka Gokulnath, Worawan B. Limpitikul, Olivia Rosina Whittaker, Kathy Luong, Christopher Azzam, Denise Gee, Matthew Hutter, Karen Flanders, Parul Sahu, Charles R. Flynn, Jonathan Brown, Danxia Yu, Evan D. Rosen, Kendall Van-Keuren Jensen, Eric R. Gamazon, Ravi Shah, Saumya Das
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-09-01
Serie:	Cell Genomics
Soggetti:	extracellular vesicles obesity plasma visceral adipose tissue BMI RNA
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666979X25001818
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!