The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity

Summary: We characterized circulating extracellular vesicles (EVs) in obese and lean humans, identifying transcriptional cargo differentially expressed in obesity (277 unique genes; false discovery rate < 10%). Since circulating EVs may have broad origin, we compared this obesity EV transcriptome wi...

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المؤلفون الرئيسيون:	Emeli Chatterjee, Michael J. Betti, Quanhu Sheng, Phillip Lin, Margo P. Emont, Guoping Li, Kaushik Amancherla, Marta Garcia-Contreras, Priyanka Gokulnath, Worawan B. Limpitikul, Olivia Rosina Whittaker, Kathy Luong, Christopher Azzam, Denise Gee, Matthew Hutter, Karen Flanders, Parul Sahu, Charles R. Flynn, Jonathan Brown, Danxia Yu, Evan D. Rosen, Kendall Van-Keuren Jensen, Eric R. Gamazon, Ravi Shah, Saumya Das
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-09-01
سلاسل:	Cell Genomics
الموضوعات:	extracellular vesicles obesity plasma visceral adipose tissue BMI RNA
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2666979X25001818
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!