HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5

HIV-1 infection activates microglia and triggers neuroinflammation, which is the primary cause of HIV-associated neurological complications. Our previous study demonstrated that HIV-1 infection upregulates m6A modification in microglia, and in this study, we investigated the underlying regulatory me...

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Egile Nagusiak:	Qian Peng, Weiling Li, Feng Qian, YinYing Zhu, Song Hu, Yingying Shi, Yiyuan Xia, Wei Liu, Xiji Shu, Pin Wan, Yuchen Liu, Binlian Sun
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis Group 2026-12-01
Saila:	Virulence
Gaiak:	HIV-1 Vpr m6A ALKBH5 microglial activation
Sarrera elektronikoa:	https://www.tandfonline.com/doi/10.1080/21505594.2026.2645908
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