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The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells

Abstract Background Graphene oxide (GO) nanoparticles (NPs) have been widely applied in various fields, especially in biomedical applications. Extensive studies have suggested that GO can pass through the blood–brain barrier (BBB) and induce abnormal autophagy and cytotoxicity in the central nervous...

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Bibliografische Detailangaben
Hauptverfasser: Chao Zhang, Xiaoli Feng, Longwen He, Yaqing Zhang, Longquan Shao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-03-01
Schriftenreihe:Journal of Nanobiotechnology
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Online-Zugang:http://link.springer.com/article/10.1186/s12951-020-00605-6
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