T cell differentiation drives the negative selection of pathogenic mitochondrial DNA variants
Fluorescently activated cell-sorting coupled with high-throughput single cell mtDNA sequencing reveals enhanced negative selection of pathogenic mtDNA variants in T cells, with more mature, memory cells exhibiting lower mutation levels than their naïve counterparts. Pathogenic mitochondrial DNA (mtD...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Life Science Alliance LLC
2023-11-01
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| Ráidu: | Life Science Alliance |
| Liŋkkat: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302271 |
| Fáddágilkorat: |
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