Integrative in silico and in vitro approach for clarifying mode of action to activate estrogen receptor alpha and lipid accumulation by methiocarb
Disruption of estrogen receptor alpha (ERα) by endocrine-active pesticides may contribute to lipid metabolic dysregulation. We aimed to clarify the docking dynamics of methiocarb with ERα and evaluate its potential to induce lipid accumulation through ERα activation using non-animal testing systems....
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2025-09-01
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| Serier: | Ecotoxicology and Environmental Safety |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S0147651325011443 |
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