Integrative in silico and in vitro approach for clarifying mode of action to activate estrogen receptor alpha and lipid accumulation by methiocarb

Disruption of estrogen receptor alpha (ERα) by endocrine-active pesticides may contribute to lipid metabolic dysregulation. We aimed to clarify the docking dynamics of methiocarb with ERα and evaluate its potential to induce lipid accumulation through ERα activation using non-animal testing systems....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Da-Hyun Jeong, Rajesh Kumar Pathak, Eunhee Lee, Jun-Mo Kim, Hee-Seok Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-09-01
Цуврал:	Ecotoxicology and Environmental Safety
Нөхцлүүд:	Methiocarb Estrogen receptor alpha Binding affinity Agonist Lipid accumulation
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0147651325011443
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!